Body Loadings and Health Assessment…(Janet K. Y.,
Teledjol.com - Sunday March 23, 2008
body loadings and health risk assessment of polychlorinated dibenzo-p-dioxins
Review and Comments by Macceau Medozile (March 2008).
In 2007, Janet K.Y. [et al.] published a research paper (in Environmental Science Technology) on body loadings and health risk assessment of polychlorinated dibenzo-p-dioxins (PCDD/Fs) and dibenzofurans at an intensive electronic waste recycling site in China. The primary objective of that case-control study was to carry out a health risk assessment in order to investigate body burdens of dioxins of local residents at Taizhou (TZ) region, since China receives about 70% of the industrial world e-waste and discarded 4 million Personal Computers (PC) annually.
E-waste recycling in China is done by rudimentary methods such as burning wire piles to recover metals, melting circuit boards over coal grills to release valuable chips, cooking computer cases to remove combustible plastics, etc. Ante-studies have indicated that uncontrollable burning and waste disposal are likely to cause serious threats to workers’ health and local residents.
The investigators targeted a case group of child-bearing-aged women (24 +/-
2 >> 83 yrs. old) at an e-waste site (Taizhou), from which 40% were primiparae (first time mother) and a reference site (Lin’an city, Zhejiang Province) located at 245 km from TZ, where about the same age group women (24 +/-
2 >> 35 trs. old) was targeted; but this time, the entire population was primiparae. Human milk, placenta and hair samples were collected at each study site from 10 women. The criteria of selection was based upon subject’s residence (living in study site at least for 2 years) and willingness to donating sufficient hair and milk specimen for chemical analysis; an informed consent was completed prior to the specimen collection. Additionally, socio-demographic data and food consumption habits of the study population were obtained through direct interviews and questionnaires.
About 100 mL of human milk (breast milk) was collected 4 ½ days after birth, the placenta was collected the day of delivery and about 3 grams of hair _ sampled from near the scalp and the nape of the neck _ was also collected the first day after delivery. All the specimens were frozen immediately after collection and stored at -20o C until chemical analyses were conducted. Levels of PCDD/Fs were indicated as mass concentration and toxic equivalency (TEQ) of the World Health Organization’s model of 1998. The body burdens were expressed as pictogram (10-12 g.) of dioxin, TEQ per gram of fat in human milk and placenta.
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